FDA Approves Botox to Treat Specific Form of Urinary Incontinence

SILVER SPRING, Md., Aug. 24, 2011 /PRNewswire-USNewswire/ — The U.S. Food and Drug Administration today approved Botox (onabotulinumtoxinA) injection to treat urinary incontinence in people with neurologic conditions such as spinal cord injury and multiple sclerosis who have overactivity of the bladder.

Uninhibited urinary bladder contractions in people with some neurological conditions can lead to an inability to store urine. Current management of this condition includes medications to relax the bladder and use of a catheter to regularly empty the bladder. Continue Reading »

Botox to treat urinary incontinence in spinal cord injury?

Urinary incontinence in spinal cord injury patients could be treated using Botox, new evidence suggests.

Allergen Inc has announced that the Irish Medicines Board supports the use of this treatment to treat urinary incontinence in spinal cord injury and multiple sclerosis patients.

Many patients with these conditions have neurogenic detrusor overactivity, meaning their bladders contract during the filling stage, when they should be relaxed. Continue Reading »

Neurogenic bladder overactivity improved with botulinum toxin A injections

NEW YORK (Reuters Health) – Injections of onabotulinumtoxinA, better known as Botox, significantly reduce urinary incontinence due to neurogenic detrusor overactivity in patients with spinal cord injury or multiple sclerosis, a Canadian team reports.

There have been only a couple of randomized controlled trials of intravesical onabotulinumtoxinA injections in this setting, note Dr. Sender Herschorn, at the University of Toronto, Ontario, and colleagues in the June issue of the Journal of Urology. Continue Reading »

BOTOX(R) (OnabotulinumtoxinA) Receives FDA Approval for Treatment of Upper Limb Spasticity in Adults

IRVINE, Calif., Mar 09, 2010 (BUSINESS WIRE) — Allergan, Inc. (NYSE: AGN) today announced that the United States Food and Drug Administration (FDA) has approved BOTOX^(R) (onabotulinumtoxinA) for the treatment of increased muscle stiffness in the elbow, wrist and fingers in adults with upper limb spasticity.

Spasticity is a debilitating condition impacting approximately 1 million Americans¹, many of whom suffer from spasticity in the upper limbs following a stroke. Upper limb spasticity may also occur following a spinal cord or traumatic brain injury or in patients affected by multiple sclerosis or adults with a history of cerebral palsy. Continue Reading »

Botox Injections Bring Relief to Victims of Stroke, Spine, Brain Injury

Best known for its use by individuals, celebrities and models to stave off “Father Time” and eliminate facial lines and wrinkles, the Botox injection is gaining increasing attention for its use in the treatment of a debilitating and painful condition known as spastic paralysis.

Also referred to as Spasticity, spastic paralysis often occurs following a stroke, spinal cord injury, or brain injury. It is estimated that spasticity affects from 19 to 38 percent of stroke patients, often affecting the hands and wrists. Spastic paralysis results from the damage to the portion of the nervous system that controls and coordinates the movement of voluntary muscles (which are the muscles that allow us to walk, throw a ball, grip a pen, play the piano, sit in a chair, etc.) Spastic paralysis leads to stiffness and lack of mobility in these muscles, disrupting mobility, reclining as well as dressing, hygiene, washing, and other activities of daily living. Continue Reading »

Urologist Uses Botox to Treat Debilitating Condition

Newswise — Eight years ago, Lynette Kunz suffered a severe spinal cord injury that left her a quadriplegic and sufferer of involuntary bladder contractions. The condition constantly interfered with her daily life.

“I can somewhat detect when my bladder is full, but I have a much shorter time span for getting to the bathroom than someone with a normal bladder,” said Ms. Kunz, 42. “I could not sit down for an entire meal at a restaurant because I was in constant fear of suffering an embarrassing incident.”

Now, thanks to a procedure performed at UT Southwestern Medical Center, Ms. Kunz has regained control of her bladder by receiving injections of botulinum toxin A, commonly known as Botox. Continue Reading »

Use of Botox® soon after spinal injury studied as way to prevent overactive bladder

HOUSTON — (October 18, 2007) — Can Botox®, used early, help spinal cord injury patients who have an overactive bladder?

Dr. Christopher Smith, assistant professor of urology at Baylor College of Medicine in Houston, hopes a federally funded study conducted in conjunction with Memorial Hermann/The Institute for Rehabilitation and Research in Houston, will answer the question. BCM is one of 10 sites participating in the national study.

Spinal cord injuries from a variety of accidents affect approximately 250,000 Americans. Continue Reading »

Fighting spasticity

Doctors increasingly implant pumps, inject Botox to relieve muscle spasms

Spokane Physiatrist Dr. Karen Stanek says a fast-growing number of people here are using two little-known tools in the fight against a debilitating muscle-contraction problem known as Spasticity.

She says usage of implantable medicine pumps to treat spasticity has doubled in the Spokane-Coeur d’Alene area in the last four years, and the use of Botox injections for the same reason has doubled in the past two years. Continue Reading »

‘I will walk again’

DAP chairman Karpal Singh has been wheelchair-bound since an auto accident last January. During his hospitalisation, he and his family downplayed the severity of his injuries. For the first time, he tells CHIN MUI YOON how he survived the ordeal and how he is coping with life as a disabled person.

PARLIAMENT is in full swing and veteran opposition MP Karpal Singh is in his element. Continue Reading »

Botox curbs incontinence from spinal cord injury

NEW YORK (Reuters Health) – Injections of Botox, or botulinum toxin-type A, appear useful in the treatment of drug-resistant urinary Incontinence due to traumatic spinal cord injury, UK researchers report.

In fact, lead investigator Dr. Prasad S. Patki told Reuters Health, “Botulinum toxin A has had a profound impact on the quality of life of spinal cord injury patients.”

“Certainly the weight of evidence favors its regular use,” Patki added. Continue Reading »