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Articles Tagged: Clinical Trial

INSPIRE Laboratory

Published: July 12, 2016 | Category: Links

inspire-lab-orgOur lab mission is to INSPIRE (integrate sensorimotor plasticity and interventions to promote recovery) persons with neurologic injury to regain function.

We are an interdisciplinary team of engineers, physiologists, neuroscientists, and clinicians that share a common mission: to study plasticity-inducing therapies directed at enhancing sensorimotor recovery in persons with catastrophic injury to their brain and/or spinal cord.

Dr. Arthur Jenkins giving TED-style: spinal cord injury and proposed changes

Published: June 11, 2016 | Category: Videos

Dr. Arthur L. Jenkins, III MD FACS giving a TED-style talk at the NY Symposium on Neurological Emergencies and Neurocritical Care. Continue Reading »

StemCells Ends Clinical Trial for Spinal Cord Injury due to Financial Constraints

Published: June 1, 2016 | Category: News

stemcellsinc-logoStemCells Inc., a California-based biotech company announced that they will stop developing the potential treatment for spinal cord injury after a failed mid-stage clinical trial. The company stock went down to $3.03 per share at the start of the pre-market trade.  StemCells reported that they still have $5.5 million in cash as of May 31, but they don’t have a liquidating distribution to their stockholders.

The company said that the amount that they can give to the shareholders depends on the liquid assets, any liabilities, and costs of the wind down. Continue Reading »

InCube Labs Announces $10 Million Department of Defense (DoD) Subcontract

Published: May 24, 2016 | Category: News

Incube-labsCompany will Collaborate with The University of Pittsburgh to Develop an Implantable Device for Spinal Cord Injury Patients

SAN ANTONIO, May 24, 2016 /PRNewswire/ — InCube Labs, a multi-disciplinary life sciences R&D lab, today announced that it has been awarded a subcontract from the University of Pittsburgh to help develop an implantable neuromodulation therapy to restore bladder function for spinal cord injury (SCI) patients. Continue Reading »

Cooling improves quality of life for spinal cord injury patients

Published: May 17, 2016 | Category: News | Spinal Cord Injury:

Minister John Day meets quadriplegic Craig ParsonsA study looking at reducing the severity of spinal injuries by reducing a patient’s body temperature immediately after an accident is entering a new phase amid hopes clinical trials will begin in WA next year.

Researchers believe the technique may ultimately make the difference between someone ending up having to use a wheelchair and being able to walk.

The research is being undertaken through WA’s Neurotrauma Research Program and the State Government is contributing $1 million towards it. Continue Reading »

Stem Cells vs. Spinal Cord Injuries

Published: March 22, 2016 | Category: News

Richard G FesslerA paralyzing injury to the neck during recreational activities such as horseback riding or playing football usually has permanent, lifelong effects that change a person’s life dramatically. With no options for the repair of spinal cord injuries, many are left with little hope for recovery.

Now researchers at Rush are exploring a new therapy that uses stem cells to treat spinal cord injuries within the first 14 to 30 days of injury. Rush is one of only two centers in the country currently studying this new approach. Continue Reading »

Spasticity : two potential therapeutic avenues

Published: March 17, 2016 | Category: Information

neurone_webFollowing spinal cord injury, most patients experience an exaggeration of muscle tone called spasticity, which frequently leads to physical disability.

A team at the Institut de Neurosciences de la Timone (CNRS/Aix-Marseille Université) has just identified one of the molecular mechanisms responsible for this phenomenon. It has also proposed two therapeutic solutions that have proved conclusive in animals, one of which will be tested during phase II clinical trials as early as this year. This work, published in Nature Medicineon 14 March 2016, thus opens new therapeutic avenues to reduce this physical disability.

Twelve million people throughout the world suffer from a motor disorder called spasticity. Continue Reading »

Pathway Study accepting potential Spinal Cord Injury volunteers for trial

Published: March 13, 2016 | Category: News

THE PATHWAY STUDY HAS CLOSED ENROLLMENT AS OF MAY 31 2016!

Pathway StudyResearchers are currently evaluating the potential of stem cell transplantation as a treatment for many neurological disorders, including spinal cord injury (SCI). Stem cells are unique from other cells in the body:

  • Stem cells can self-renew (make copies of themselves)
  • Stem cells can respond to signals within the body and become specialized (this is known as differentiation)

Studying stem cell transplantation for SCI may help us learn if stem cells can help either replace or repair spinal cord cells that were damaged by injury which may in turn improve spinal cord function. Continue Reading »

UPMC’s clinical trial showing promise with spinal cord injuries

Published: February 26, 2016 | Category: News | Spinal Cord Injury: , ,

Michael-FraserThree years ago, Michael Fraser broke his neck in a diving accident near his Vandergrift home but remembers little about it.

But in April, the man with quadriplegia underwent an experimental neural stem-cell procedure that wasn’t only a life-changing experience but could represent the first interventional treatment for spinal cord injuries.

Mr. Fraser, 24, now can lift himself from his wheelchair into bed without assistance. He breathes more freely and deeply and has greater core strength with better dexterity. Previously he could manage only a half-mile on his arm-powered elliptical but now does two to three miles, he said. Continue Reading »

Stem cell treatment could help paralyzed patients move

Published: January 15, 2016 | Category: News | Spinal Cord Injury:

Louis TontodonatoLouis Tontodonato’s hopes and dreams may well lie in a virtual coin flip, a digital roll of the dice.

Paralyzed from the neck down, the 20-year-old Naples, Fla., man has enrolled in the first clinical trial testing the ability of stem cells to repair spinal cord injuries and restore sensation and movement in quadriplegics. Early studies in animals and humans have had remarkable results, enabling patients to resume everyday tasks they thought had been lost forever. If those early effects are validated, the treatment has the potential to drastically improve the quality of life and independence of thousands of spinal cord injury patients. Continue Reading »