Description of Schwann Cells provided by Inner Learning Online. Larger axons passing through Peripheral nerves commonly are enclosed in sheaths called “Schwann cells.” These are tightly wound around the axons, somewhat like insulation on a wire. The smallest axons also are enclosed in Schwann cells, but they are not wound around the axons. These membranes are composed largely of lipid-protein that has a higher proportion of lipid (fat) than other cell surface membranes. This lipid-protein is called Myelin, and it forms a “myelin sheath” on the outside of an Axon. Axons that have myelin sheaths are called “myelinated” (or medullated) nerve fibers, while those that lack these sheaths are “unmyelinated” nerve fibers. Continue Reading »
Articles Tagged: Clinical Trial
When people are injured, they are often told that they have an injury at a given spinal cord level and are given a qualifier indicating the severity of injury, i.e. “complete” or “incomplete”. They may also be told that they are classified according to the American Spinal Injury Association (ASIA) Classification, as a ASIA A, B, C, or D. They may also be told that they have a bony fracture or involvement of one or more spinal segments or vertebral levels. What most people do not know is doctors are frequently confused about the definition of spinal cord injury levels, the definition of complete and Incomplete Injury, and the classification of spinal cord injury. In the early 1990′s, when I co-chaired the committee that helped define the currently accepted ASIA Classification, there was no single definition of level, completeness of injury, or classification. In this article, I will briefly address the issue of spinal cord injury levels, the definition of “complete” spinal cord injury, and the ASIA Classification approach towards spinal cord injury. Continue Reading »
SAN DIEGO — Several scientists have used embryonic or fetal stem cells to help rodents with spinal cord injuries walk again. The researchers travel the country showing videos of rats dragging their hind legs, followed by clips of them miraculously hopping around following stem-cell injections. Continue Reading »
Purdue Research Foundation has signed a license agreement with Andara Life Science Inc. The agreement grants the company exclusive commercial rights to a platform of treatment alternatives, including a medical device, a combination medical device and drug, and a series of drugs, all targeting injury and diseases of the Central Nervous System. Purdue’s patented oscillating field stimulator (OFS), which stimulates nerve Regeneration and has shown initial results in human clinical trials, forms the foundation of the treatment. Continue Reading »
By Max Showalter, Journal and Courier
A life sciences company formed just four months ago in the Purdue Research Park has been given the green light to commercialize a high-tech treatment for injury and disease of a person’s Central Nervous System. Continue Reading »
Concerted National Effort Needed To Develop New Therapies
Washington, D.C. – infoZine – Recent discoveries about the Central Nervous System’s capacity for Regeneration and repair could lead to important gains in restoring function and improving quality of life for individuals living with spinal cord injuries. A multifaceted approach to research on spinal cord injuries – one that pursues combinations of therapies and ways to treat injuries at different stages – is needed to speed progress toward a cure, says a new report from the Institute of Medicine of the National Academies. Continue Reading »
For Chaz Southard, hope exists in the form of a blue plastic bracelet.
“People naturally ask why you’re wearing the bracelet and what it’s for,” said the 25-year-old Topsfield resident who suffered a spinal cord injury two and half years ago. “It’s a talking piece more than anything else.” Continue Reading »
IRVINE, Calif. – Hans S. Keirstead might be the Pied Piper of stem cells – and not just because he makes rats walk. He also helped lure Californians to the polls last fall to approve spending $3 billion of the state’s money on embryonic stem cell research over the next decade. But he has critics who worry that he may be leading their new field too far, too soon into uncharted territory.Dr. Keirstead, an assistant professor at the University of California campus here, has been making paralyzed rats walk again, using a treatment based on human embryonic stem cells. Continue Reading »
SATURDAY, Jan. 22 (HealthDayNews) — A experimental device designed to regenerate nerve fibers in people with spinal cord injuries shows promise, says an Indiana University School of Medicine study in the January issue of the Journal of Neurosurgery.
The oscillating field stimulator (OFS) creates an electrical field in the area of damaged nerves. It was developed at Purdue University. Continue Reading »
An implantable, brain-computer interface the size of an aspirin has been clinically tested on humans by American company Cyberkinetics. The ‘BrainGate’ device can provide paralysed or Motor-impaired patients a mode of communication through the translation of thought into direct computer control. The technology driving this breakthrough in the Brain-Machine-Interface field has a myriad of potential applications, including the development of human augmentation for military and commercial purposes. Continue Reading »