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Articles Tagged: Functional Improvement

Patients with Complete Paralysis Show Additional Recovery of Arm, Hand and Finger Function at 9-months After Treatment with Asterias’ AST-OPC1

Published: June 13, 2017 | Category: News

Third patient recovers two motor levels; three of six (50%) patients in AIS-A 10 million cell cohort have now recovered two motor levels on at least one side

FREMONT, Calif., June 13, 2017 /PRNewswire/ — Asterias Biotherapeutics, Inc. (NYSE MKT: AST), a biotechnology company pioneering the field of regenerative medicine, today announced that new 9-month follow-up data from the AIS-A 10 million cell cohort in the company’s ongoing SCiStar Phase 1/2a clinical trial shows three of six (50%) patients have now recovered two levels of motor function and previously-announced improvements in arm, hand and finger function at 3-months and 6-months following administration of AST-OPC1 have been confirmed and further increased at 9-months. Continue Reading »

New discovery in spinal cord injuries shows oxygen can improve blood flow and restore motor function: U of A study

Published: May 1, 2017 | Category: News

Neuroscientists at University of AlbertaA new discovery at the University of Alberta will fundamentally alter how we view spinal cord function and rehabilitation after spinal cord injuries (SCI). Neuroscientists found that spinal blood flow in rats was unexpectedly compromised long after a spinal cord injury (chronically ischemia), and that improving blood flow or simply inhaling more oxygen produces lasting improvements in cord oxygenation and motor functions, such as walking.

Previous work had shown that while blood flow was temporarily disrupted at the injury site, it resumed rapidly, and it was more or less assumed that the blood flow was normal below the injury. This turns out to be wrong. Continue Reading »

Tendon Transfer Should Be Used More Often in Tetraplegia

Published: September 7, 2016 | Category: News | Spinal Cord Injury: , ,

tendon-tranferTendon transfer can significantly improve hand and elbow function in quadriplegic patients, but the procedure is greatly underused, according to a new study.

A review of studies by hand surgeon Professor Michael Bednar, MD, of Loyola Medicine (Maywood, IL, USA) found that an estimated 65-75% of patients with cervical spinal cord injuries could benefit from upper extremity tendon transfer surgery, but only 14% of patients actually complete the procedure. Tendon transfer surgically redirects functional muscles to do the work of muscles that are paralyzed. Depending on the extent of the spinal cord injury, tendon transfers can enable a patient to grasp objects, pinch, open the hand, and straighten the elbow. Continue Reading »

UPMC’s clinical trial showing promise with spinal cord injuries

Published: February 26, 2016 | Category: News | Spinal Cord Injury: , ,

Michael-FraserThree years ago, Michael Fraser broke his neck in a diving accident near his Vandergrift home but remembers little about it.

But in April, the man with quadriplegia underwent an experimental neural stem-cell procedure that wasn’t only a life-changing experience but could represent the first interventional treatment for spinal cord injuries.

Mr. Fraser, 24, now can lift himself from his wheelchair into bed without assistance. He breathes more freely and deeply and has greater core strength with better dexterity. Previously he could manage only a half-mile on his arm-powered elliptical but now does two to three miles, he said. Continue Reading »

Gene therapy improves limb function following spinal cord injury

Published: April 1, 2014 | Category: News

Delivering a single injection of a scar-busting gene therapy to the spinal cord of rats following injury promotes the survival of nerve cells and improves hind limb function within weeks, according to a study published April 2 in The Journal of Neuroscience. The findings suggest that, with more confirming research in animals and humans, gene therapy may hold the potential to one day treat people with spinal cord injuries. Continue Reading »

New Rehabilitation Research Demonstrates Functional Improvements in Patients with Spinal Cord Injuries

Published: October 8, 2012 | Category: News

Newswise — STONY BROOK, N.Y., October 8, 2012 – A series of rehabilitation studies published in the September 2012 issue of the Archives of Physical Medicine & Rehabilitation demonstrate that innovative treatments for individuals with spinal cord injuries can lead to significant functional improvements in patients and a higher quality of life. Continue Reading »

InVivo Therapeutics Protects And Regenerates The Spinal Cord Resulting in Functional Improvement Below the Injury

Published: June 21, 2012 | Category: Featured News | Spinal Cord Injury:

Frank Reynolds, of InVivo Therapeutics (NVIV), says the company is on the verge of unprecedented technology for the treatment of the spinal cord. The Massachusetts-based medical device company is developing regenerative and neuroprotective technologies for the treatment of spinal cord injuries. It is the first company in history to successfully demonstrate functional improvement in a paralyzed non-human primate.

Below OneMedRadio interviews Reynolds where he speaks candidly about his own injury rendering him a paraplegic, and the passion behind his work. Reynolds will be presenting InVivo’s technology at OneMedForum New York on July 12, 2012. Continue Reading »