Thursday, December 18th 2014

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Articles Tagged: Stem Cells

Scientists crack stem cell reprogramming code

Published: December 10, 2014 | Category: News

Doctor Andras NagyTORONTO – A Canadian-led international team of researchers has begun solving the mystery of just how a specialized cell taken from a person’s skin is reprogrammed into an embryonic-like stem cell, from which virtually any other cell type in the body can be generated.

The research is being touted as a breakthrough in regenerative medicine that will allow scientists to one day harness stem cells to treat or even cure a host of conditions, from blindness and Parkinson’s disease to diabetes and spinal cord injuries. Continue Reading »

German Scientists create lab-grown spinal cords

Published: November 28, 2014 | Category: News

Sonic Hedgehog proteinFor the first time, researchers in Germany have been able to create spinal cords in a Petri dish. To be more precise, they didn’t grow complete spinal cords, but neuroepithelial cysts, which are ellipsoid like and were about 60 μm in diameter. These cells express factors that are associated with spinal cord tissue and are in many ways similar to it.

Regenerative medicine is entering its golden age, with new techniques showing more and more promise; the list of tissues that can be grown from scratch and then used continues to grow, and it may not be long before we can add spinal cells to the list. Continue Reading »

Critical Mass of Stem Cells Sets Off Embryonic Development in the Lab

Published: November 5, 2014 | Category: News

UCambridge Early Stage EmbryoWhen stem cells are propagated in the laboratory, they typically differentiate into one or another specialized cell type, usually forming cell masses that show little organization or spatial coherence. Exceptions include the emergence, in culture, of retinal and anterior cortex-like tissues. For the most part, however, stem cell aggregates in the laboratory prefer to remain lumps.

Despite coaxing, they refuse to organize themselves into structures that resemble embryos. In particular, they avoid taking the earliest steps of embryonic development—axis formation and gastrulation, the organized movement of cells that, using the initial axis as a reference, positions the head and the tail, the front and the back. Continue Reading »

Stem cells from human embryos prove safe, improve vision -study

Published: October 14, 2014 | Category: News

(Reuters) – The longest-running trial of stem cells derived from a human embryo found that the cells caused patients none of the problems scientists feared, such as forming tumors, and reversed partial blindness in about half the eyes receiving transplants, researchers reported on Tuesday. Continue Reading »

StemCells Inc. Initiates Phase 2 Clinical Trial In Cervical Spinal Cord Injury

Published: October 7, 2014 | Category: News

stemcellsinc-logoNEWARK, Calif., Oct. 7, 2014 (GLOBE NEWSWIRE) — StemCells, Inc. (Nasdaq:STEM), a world leader in the research and development of cell based therapies for the treatment of disorders of the central nervous system, announced today that it has initiated its Pathway® Study, a Phase II proof of concept clinical trial using its proprietary HuCNS-SC® platform of human neural stem cells for the treatment of cervical spinal cord injury (SCI). Approximately 1.3 million people in the United States report being paralyzed due to an SCI, and there currently are no effective treatments available. Approximately 56% of the spinal cord injuries occur in the cervical region. Overall, approximately 13% of SCI patients have no mobility and 35% have limited mobility after the traumatic injury. Continue Reading »

Stem cells use ‘first aid kits’ to repair damage

Published: September 18, 2014 | Category: News

Mesenchymal stem cellStem cells hold great promise as a means of repairing cells in conditions such as multiple sclerosis, stroke or injuries of the spinal cord because they have the ability to develop into almost any cell type. Now, new research shows that stem cell therapy can also work through a mechanism other than cell replacement.

In a study published today in Molecular Cell, a team of researchers led by the University of Cambridge has shown that stem cells “communicate” with cells by transferring molecules via fluid filled bags called vesicles, helping other cells to modify the damaging immune response around them. Continue Reading »

Scientists recreate spinal, muscle and bone tissue with stem cells

Published: August 27, 2014 | Category: News

d068415028-jpgIt’s one of the latest efforts to remake tissue in the lab. The discovery could lead to more research into human development and disease progression.

Using stem cells, scientists have recreated the cells that form an embryo’s spinal cord, muscle and bone tissue. This will help researchers further study embryonic development and possibly, one day, disease progression.

Neuro-mesodermal progenitors (NMPs) — the particular cells that form the spinal cord, muscle and skeleton — begin their transformation once given the go-ahead by certain chemical signals in the body. Continue Reading »

Stem cell breakthrough for ‘Cinderella cells’

Published: August 27, 2014 | Category: News

stem-cellsThe specialized cells that go on to form the spinal cord, muscle and bone tissue in a growing embryo have been produced in the laboratory using stem cells for the first time.

The spinal cord, muscle and skeleton cells are all formed from cells called neuro-mesodermal progenitors (NMPs). A process of carefully timed chemical signals in the growing embryo instructs NMPs to turn into the different cells required for these body parts. Continue Reading »

Quadriplegic Perry Cross on why he travels to India as a ‘stem cell tourist’ to find a cure for paralysis

Published: July 16, 2014 | Category: News | Spinal Cord Injury:

Perry Cross a C2 quadriplegicPERRY Cross was just 19 when he suffered a devastating neck injury that should have killed him.

Doctors told his family he had months to live, and if he survived beyond that the best he could hope for as a quadriplegic was just 10 years.

Now almost 20 years later, Mr Cross is still cheating death after a rugby accident that left him unable to walk, talk, eat, move his head or even breathe without the help of a respirator. Continue Reading »

Stem-cell advances may quell ethics debate

Published: June 22, 2014 | Category: Featured News

Robert WaddellRobert Waddell says he’s glad the stem cells that healed him came from “a guy who was 50 years old” and not a human embryo.

As a Catholic, Waddell opposes the destruction of embryos and didn’t want to rely on embryonic stem cells to cure his kidney disease. But he avoided this moral dilemma by getting bone marrow stem cells from a friend who donated a kidney as part of a University of Louisville study.

“It has nothing to do with embryonic stem cells,” said Waddell, a 47-year-old father of four. “That made it a lot easier.” Continue Reading »