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Articles Tagged: Stem Cells

Help shape the future of SCI treatment

Published: April 20, 2016 | Category: Information

Pathway-LogoThe path to recovery from spinal cord injury (SCI) is full of challenges.

If you’re interested in taking part in research to evaluate investigational therapies for SCI, you may be interested in a clinical research study called Pathway that is evaluating the potential of neural stem cells to treat cervical spinal cord injury (cSCI).

What is the Pathway study?

The purpose of the Pathway Study is to evaluate the safety and potential benefit of neural stem cell transplantation for people with cSCI. If you are eligible for the study and if you choose to participate, your participation will last approximately 12 months. Continue Reading »

The Use of Cell Transplantation in Spinal Cord Injuries

Published: April 14, 2016 | Category: Information

stem-cells-for-spinal-cord-injuryOverview
The spinal cord is often called as a delicate tissue, which is secured inside very hard vertebrae of spinal column. The spinal cord and brain is seen forming the central nervous system of our body. The spinal cord is basically made up of millions of nerve cells, which carry a number of signals to our brain and out over the other parts of human body. Unfortunately with issues like injuries with accident and with age or other ailments the spinal cord can end up getting injured. There are certain spinal cord injuries, which can be fixed with the help of treatment options like cell transplantation. Now, let us dig in deep into this treatment option in the following paragraphs: Continue Reading »

5 Things to Know About Spinal Cord Injury

Published: April 8, 2016 | Category: Information

Human Spine x-rayA spinal cord injury can be a life-altering event for the person who sustains it as well as for their loved ones. Given the potential for lifelong disability, it is vital that the facts about these kinds of injuries be clearly understood. Here are five key things to know about them: Continue Reading »

Stem cells used to successfully regenerate damage in corticospinal injury

Published: March 28, 2016 | Category: News

robust-corticospinal-regenerationFor first time, researchers show functional benefit in animal model of key motor control system

Writing in the March 28, 2016 issue of Nature Medicine, researchers at University of California, San Diego School of Medicine and Veterans Affairs San Diego Healthcare System, with colleagues in Japan and Wisconsin, report that they have successfully directed stem cell-derived neurons to regenerate lost tissue in damaged corticospinal tracts of rats, resulting in functional benefit. Continue Reading »

Stem Cells vs. Spinal Cord Injuries

Published: March 22, 2016 | Category: News

Richard G FesslerA paralyzing injury to the neck during recreational activities such as horseback riding or playing football usually has permanent, lifelong effects that change a person’s life dramatically. With no options for the repair of spinal cord injuries, many are left with little hope for recovery.

Now researchers at Rush are exploring a new therapy that uses stem cells to treat spinal cord injuries within the first 14 to 30 days of injury. Rush is one of only two centers in the country currently studying this new approach. Continue Reading »

Pathway Study accepting potential Spinal Cord Injury volunteers for trial

Published: March 13, 2016 | Category: News

Pathway StudyResearchers are currently evaluating the potential of stem cell transplantation as a treatment for many neurological disorders, including spinal cord injury (SCI). Stem cells are unique from other cells in the body:

  • Stem cells can self-renew (make copies of themselves)
  • Stem cells can respond to signals within the body and become specialized (this is known as differentiation)

Studying stem cell transplantation for SCI may help us learn if stem cells can help either replace or repair spinal cord cells that were damaged by injury which may in turn improve spinal cord function. Continue Reading »

UPMC’s clinical trial showing promise with spinal cord injuries

Published: February 26, 2016 | Category: News | Spinal Cord Injury: , ,

Michael-FraserThree years ago, Michael Fraser broke his neck in a diving accident near his Vandergrift home but remembers little about it.

But in April, the man with quadriplegia underwent an experimental neural stem-cell procedure that wasn’t only a life-changing experience but could represent the first interventional treatment for spinal cord injuries.

Mr. Fraser, 24, now can lift himself from his wheelchair into bed without assistance. He breathes more freely and deeply and has greater core strength with better dexterity. Previously he could manage only a half-mile on his arm-powered elliptical but now does two to three miles, he said. Continue Reading »

Controlling Immune Response in Spinal Cord Injury Patients

Published: January 27, 2016 | Category: News

human's thoracic-lumbar spine and inflammation at spineThe immune system of spinal cord injury patients can be controlled using a family of therapeutic stem cells, according to findings published in Scientific Reports.

Researchers from Case Western Reserve University studied the therapeutic stem cells, known as multipotent adult progenitor cells (MAPC) in order to observe their qualities and effects on spinal cord injury patients’ immune systems. Continue Reading »

One Small Step

Published: January 25, 2016 | Category: News | Spinal Cord Injury: ,

Darek FidykaA paraplegic undergoes pioneering surgery.

When a spinal cord is damaged, location is destiny: the higher the injury, the more severe the effects. The spine has thirty-three vertebrae, which are divided into five regions—the coccygeal, the sacral, the lumbar, the thoracic, and the cervical. The nerve-rich cord traverses nearly the entire length of the spine. The nerves at the bottom of the cord are well buried, and sometimes you can walk away from damage to these areas. In between are insults to the long middle region of the spine, which begins at the shoulders and ends at the midriff. Continue Reading »

Stem cell treatment could help paralyzed patients move

Published: January 15, 2016 | Category: News | Spinal Cord Injury:

Louis TontodonatoLouis Tontodonato’s hopes and dreams may well lie in a virtual coin flip, a digital roll of the dice.

Paralyzed from the neck down, the 20-year-old Naples, Fla., man has enrolled in the first clinical trial testing the ability of stem cells to repair spinal cord injuries and restore sensation and movement in quadriplegics. Early studies in animals and humans have had remarkable results, enabling patients to resume everyday tasks they thought had been lost forever. If those early effects are validated, the treatment has the potential to drastically improve the quality of life and independence of thousands of spinal cord injury patients. Continue Reading »

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