Chronic pain and loss of bladder control are among the most devastating consequences of spinal cord injury, rated by many patients as a higher priority for treatment than paralysis or numbness. Now a UC San Francisco team has transplanted immature human neurons into mice with spinal cord injuries, and shown that the cells successfully wire up with the damaged spinal cord to improve bladder control and reduce pain. This is a key step towards developing cell therapies for spinal cord injury in humans, say the researchers, who are currently working to develop the technique for future clinical trials. Continue Reading »
Articles Tagged: Stem Cells
An experimental stem cell therapy developed by Asterias Biotherapeutics restored some movement to patients paralyzed by recent spinal cord injuries, according to interim data from a small study being presented on Wednesday.
One of the five patients in the trial regained use of both arms and hands, and is now able to feed himself, send texts on a phone and operate a wheelchair, the Fremont, California-based company said.
Three months after the cells were implanted, the study met its efficacy goal of two patients regaining return of two motor levels of functioning on at least one side of their body, the company said.
All five people in the study have experienced some upper extremity improvement so far, Asterias said. Continue Reading »
Paralyzed Man Regains Use of Arms and Hands After Experimental Stem Cell Therapy at Keck Hospital of USC
Initial Results Offer Hope for Patients to Reclaim Independence After Suffering Severe Spinal Injury
LOS ANGELES, Sept. 7, 2016 /PRNewswire/ — Keck Medical Center of USC today announced that a team of doctors became the first in California to inject an experimental treatment made from stem cells, AST-OPC1, into the damaged cervical spine of a recently paralyzed 21-year-old man as part of a multi-center clinical trial. Continue Reading »
Stem Cell treatment or the Human Embryonic Stem Cells (HESC) is effective in the replacement of damaged neurons, re-establishment of lost axonal connections, and providing of neuro-protective factors to allow the healing and recovery of spinal cord injury, revealed a study.
Stem Cell treatment or the Human Embryonic Stem Cells (HESC) is effective in the replacement of damaged neurons, re-establishment of lost axonal connections, and providing of neuro-protective factors to allow the healing and recovery of spinal cord injury, revealed a study. Continue Reading »
StemCells Inc., a California-based biotech company announced that they will stop developing the potential treatment for spinal cord injury after a failed mid-stage clinical trial. The company stock went down to $3.03 per share at the start of the pre-market trade. StemCells reported that they still have $5.5 million in cash as of May 31, but they don’t have a liquidating distribution to their stockholders.
The company said that the amount that they can give to the shareholders depends on the liquid assets, any liabilities, and costs of the wind down. Continue Reading »
An experimental procedure aimed at repairing spinal cord injuries is showing promise. It uses stem cells in the damaged areas in hopes of restoring function and movement.
And for one patient, it is promising.
On April 9, 2013, James Mason was an accident waiting to happen.
“There was nothing we could have done to change that night,” said Bob Gambuti. Continue Reading »
New Hope for Paralyzed Patients?
If you have a spinal cord injury, recent reports on stem cell therapy look like a dream come true. Like wire spliced into a severed cable, stem cells could restore communication between your body and your brain.
After endless numbness, you might once again feel the grass between your toes or the caress of a lover. After an eternity of motionlessness, you might rise from your chair or hoist a glass of wine to your lips. Continue Reading »
The path to recovery from spinal cord injury (SCI) is full of challenges.
If you’re interested in taking part in research to evaluate investigational therapies for SCI, you may be interested in a clinical research study called Pathway that is evaluating the potential of neural stem cells to treat cervical spinal cord injury (cSCI).
What is the Pathway study?
The purpose of the Pathway Study is to evaluate the safety and potential benefit of neural stem cell transplantation for people with cSCI. If you are eligible for the study and if you choose to participate, your participation will last approximately 12 months. Continue Reading »
The spinal cord is often called as a delicate tissue, which is secured inside very hard vertebrae of spinal column. The spinal cord and brain is seen forming the central nervous system of our body. The spinal cord is basically made up of millions of nerve cells, which carry a number of signals to our brain and out over the other parts of human body. Unfortunately with issues like injuries with accident and with age or other ailments the spinal cord can end up getting injured. There are certain spinal cord injuries, which can be fixed with the help of treatment options like cell transplantation. Now, let us dig in deep into this treatment option in the following paragraphs: Continue Reading »
A spinal cord injury can be a life-altering event for the person who sustains it as well as for their loved ones. Given the potential for lifelong disability, it is vital that the facts about these kinds of injuries be clearly understood. Here are five key things to know about them: Continue Reading »