Articles Tagged: Stem Cells
November 21, 2013 | Category: News
| Spinal Cord Injury: T-10
After laboratory mice received a contusive spinal cord injury at the T10 level, low and high doses of neural stem/progenitor cells (NS/PCs) derived from fetal bioluminescent-labeled transgenic mice were injected into four groups of mice at either the lesion epicenter or at rostral and caudal sites. A control group was similarly injected with phosphate buffered saline. The mice receiving the NS/PC cells experienced motor functional recovery while those in the control group did not.
It is known that transplanting neural stem/progenitor cells (NS/PCs) into the spinal cord promotes functional recovery after spinal cord injury (SCI). However, which transplantation sites provide optimal benefit? Continue Reading »
September 11, 2013 | Category: News
LONDON (Reuters) – Scientists have succeeded in generating new stem cells in living mice and say their success opens up possibilities for the regeneration of damaged tissue in people with conditions ranging from heart failure to spinal cord injury.
The researchers used the same “recipe” of growth-boosting ingredients normally used for making stem cells in a petri dish, but introduced them instead into living laboratory mice and found they were able to create so-called reprogrammed induced pluripotent stem cells (iPS cells). Continue Reading »
August 26, 2013 | Category: News
Washington, August 26 (ANI): Researchers have discovered a new technique called Biphasic Electrical stimulation (BES), a non-chemical procedure, that they believe can be used for spinal cord injury patients in the future.
Transplantation of Stem Cells is a potential clinical therapy for repair and regeneration of injured spinal cord, and brings new hope for patients. However, the survival rate of transplanted cells is relatively low as the cells are particularly vulnerable to apoptosis in the spinal cord. Continue Reading »
February 12, 2013 | Category: News
StemCells, Inc. Announces First Patient Cohort Completes Spinal Cord Injury Trial – Gains in Sensory Function Persist 12 Months After Stem Cell Transplant
NEWARK, Calif., Feb. 12, 2013 (GLOBE NEWSWIRE) — StemCells, Inc. (Nasdaq:STEM) today announced that the twelve-month data from the first patient cohort in the Company’s Phase I/II clinical trial of its proprietary HuCNS-SC® product candidate (purified human neural stem cells) for chronic spinal cord injury continued to demonstrate a favorable safety profile, and showed that the considerable gains in sensory function observed in two of the three patients at the six-month assessment have persisted. Continue Reading »
September 25, 2012 | Category: News
European researchers have made significant progress in the attempt to treat spinal cord injuries using stem cell therapy. Although there have been several attempt to cure spinal cord injury patients, the results were not so encouraging.
Now, however, the project “From stem cell technology to functional restoration after spinal cord injury ‘(Rescue) has promising results so far. Continue Reading »
September 7, 2012 | Category: News
(CNN) — As the sun rose over France on August 13, 2011, Knut Olstad was looking forward to continuing his bicycle journey along the Tour de France route. But by the end of the day, the vacation had taken a terrible turn that would change his life.
The 46-year-old financial consultant from Norway doesn’t remember much about the accident that left him paralyzed from the chest down. He was shown pictures of himself lying on the ground with a broken back after being catapulted from his bike while trying to avoid a collision with a car. Continue Reading »
August 23, 2012 | Category: News
After 26 years in a wheel chair William Orr is walking. It is with the assistance of a walker, but he is walking. Orr is walking to get his mail, he is walking to rehab from his car and he is planning on walking into his 35th high school reunion.
After 26 years in a wheel chair William Orr is walking. Granted it is with the assistance of a walker, but he is walking. Orr is walking to get his mail, he is walking to rehab from his parked car and he is planning on walking into his 35th high school reunion. Continue Reading »
May 17, 2012 | Category: News
Thirty Percent of Patients Show Improved Functioning after Stem Cell Therapy
Philadelphia, Pa. (May 17, 2012) – One of the first long-term studies of stem cell treatment for spinal cord injury shows significant functional and other improvements in three out of ten patients, reports a study in the May issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. Continue Reading »
Given that the firm with the most money has just quit, questions about how to succeed are rampant.
Geron, a pioneer in stem cell research founded in 1990, announced on November 14 that it was halting its stem cell therapeutics programs to conserve funds. It plans on laying off 38% of its 175-person staff and is seeking partners to take on the programs’ assets.
Geron had been developing cell products from differentiated human embryonic stem cells (hESCs) for multiple indications. The company is viewed as the leader in stem cell therapies because of its patents on technology used to grow, manipulate, and inject stem cells into the human body. It helped finance researchers at the University of Wisconsin who first isolated human embryonic stem cells in 1998, allowing the cells to be grown in the laboratory. Continue Reading »
A District Court judge in the US has dismissed a lawsuit that sought to ban federal funding for human embryonic stem cell (hESC) research. The decision, by Judge Royce Lambeth, is the latest development in the case of Sherley v Sebelius – a landmark lawsuit filed against the US’s state-funded National Institutes of Health (NIH) in 2009.
The case was brought by two scientists, Dr James Sherley and Dr Theresa Deisher, who opposed changes to NIH guidelines that expanded hESC research following an executive order by President Barack Obama. This order eased restrictions on hESC research imposed by the previous President, George W. Bush, but the pair, who both work with adult stem cells, argued the new guidelines violated the Dickey-Wicker Amendment. This is a 1996 law which bars the use of federal funds for ‘research in which a human embryo or embryos are destroyed’. Continue Reading »