Wheelchair rugby is a high-octane team contact sport changing the lives and mental health of the spinal cord injury patients who play it. Continue Reading »
Articles Tagged: Study
New discovery in spinal cord injuries shows oxygen can improve blood flow and restore motor function: U of A study
A new discovery at the University of Alberta will fundamentally alter how we view spinal cord function and rehabilitation after spinal cord injuries (SCI). Neuroscientists found that spinal blood flow in rats was unexpectedly compromised long after a spinal cord injury (chronically ischemia), and that improving blood flow or simply inhaling more oxygen produces lasting improvements in cord oxygenation and motor functions, such as walking.
Previous work had shown that while blood flow was temporarily disrupted at the injury site, it resumed rapidly, and it was more or less assumed that the blood flow was normal below the injury. This turns out to be wrong. Continue Reading »
ROCHESTER, Minn. – Mayo Clinic researchers used electrical stimulation on the spinal cord and intense physical therapy to help a man intentionally move his paralyzed legs, stand and make steplike motions for the first time in three years.
The case, the result of collaboration with UCLA researchers, appears today in Mayo Clinic Proceedings. Researchers say these results offer further evidence that a combination of this technology and rehabilitation may help patients with spinal cord injuries regain control over previously paralyzed movements, such as steplike actions, balance control and standing. Continue Reading »
Discovery could be key to treating brain and spinal cord injury
A foray into plant biology led one researcher to discover that a natural molecule can repair axons, the thread-like projections that carry electrical signals between cells. Axonal damage is the major culprit underlying disability in conditions such as spinal cord injury and stroke.
Andrew Kaplan, a PhD candidate at the Montreal Neurological Institute and Hospital of McGill University, was looking for a pharmacological approach to axon regeneration, with a focus on 14-3-3, a family of proteins with neuroprotective functions that have been under investigation in the laboratory of Dr. Alyson Fournier, professor of neurology and neurosurgery and senior author on the study. Continue Reading »
Patients suffering from complete spinal cord injuries have little to no treatment options that provide meaningful improvement in patient outcomes.
Cambridge, Mass.-based InVivo Therapeutics is trying to change that. Co-founded in 2005 by MIT professor Robert Langer, and surgeon-scientists Joseph Vacanti, M.D., the company has developed a small, bioresorbable and biocompatible device called the Neuro-Spinal Scaffold, to help patients with complete thoracic spinal cord injuries regain some function. Continue Reading »
In a Stanford-led research report, three participants with movement impairment controlled an onscreen cursor simply by imagining their own hand movements.
A clinical research publication led by Stanford University investigators has demonstrated that a brain-to-computer hookup can enable people with paralysis to type via direct brain control at the highest speeds and accuracy levels reported to date. Continue Reading »
Early clinical trial results announced offer new hope in regenerative medicine
A new therapy to treat spinal cord injuries in people who have lost all motor and sensory function below the injury site shows additional motor function improvement at 6-months and 9-months following treatment with 10 million AST-OPC1. The positive efficacy results from an ongoing research study were announced on Jan. 24 in a conference held by Asterias Biotherapeutics, Inc., the biotechnology company that manufactures AST-OPC1. Continue Reading »
UCLA scientists test electrical stimulation that bypasses injury; technique boosts patient’s finger control, grip strength up to 300 percent
A spinal stimulator being tested by doctors at Ronald Reagan UCLA Medical Center is showing promise in restoring hand strength and movement to a California man who broke his neck in a dirt bike accident five years ago.
In June, Brian Gomez, now 28, became one of the first people in the world to undergo surgery for the experimental device. Continue Reading »
Researchers have developed a urine test revealing the presence of a neurotoxin that likely worsens the severity and pain of spinal cord injuries, suggesting a new tool to treat the injuries.
The neurotoxin, called acrolein, is produced within the body after nerve cells are damaged, increasing pain and triggering a cascade of biochemical events thought to worsen the injury’s severity. Continue Reading »
The gut microbiome undergoes changes after a patient suffers a spinal cord injury, according to a new study.
Researchers from The Ohio State University Wexner Medical Center used mice models of spinal cord injury in order to determine whether gut bacteria dysbiosis – or, functional interruption – affects the recovery of neurological function in patients after a traumatic spinal cord injury. The researchers wrote that this dysbiosis can both cause and exacerbate a number of diseases. The study authors studied changes in the mice’s microbiomes after their injuries for a month to predict the range of their locomotor impairment, they wrote. Continue Reading »